Khortytsia (Ukrainian: Хо́ртиця, Khortyts'a, Russian: Хо́ртица, Khortitsa, Polish: Chortyca) is a national cultural reserve (sanctuary) located on one of the largest islands of the Dnieper river, in Ukraine.
The island has played an important role in the history of Ukraine, specially in the history of the Zaporozhian Cossacks.